An investigation of beta-secretase activity and regulation in Alzheimer's disease
Alzheimer's disease (AD) is the most common cause of dementia, characterized by the • presence of extracellular amyloid plaques and intracellular tangles in the brain. The principal component of amyloid plaques is the amyloid 13 (A13) peptide, cleaved from amyloid precursor protein (APP) by...
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Queen's University Belfast
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486241 |