Cervical epithelial-specific delivery of small interfering RNA (siRNA); potential therapy for cervical carcinoma
KNA interference (RNAi) is a ubiquitous gene silencing mechanism, in which small interfering RNAs (siRNAs) guide sequence-specific cleavage of mRNA transcripts. Since naked siRNAs are inefficiently internalised by mammalian cells, successful delivery of siRNA to target cells is the biggest challenge...
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University of Oxford
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490105 |