Cervical epithelial-specific delivery of small interfering RNA (siRNA); potential therapy for cervical carcinoma

Cervical epithelial-specific delivery of small interfering RNA (siRNA); potential therapy for cervical carcinoma

KNA interference (RNAi) is a ubiquitous gene silencing mechanism, in which small interfering RNAs (siRNAs) guide sequence-specific cleavage of mRNA transcripts. Since naked siRNAs are inefficiently internalised by mammalian cells, successful delivery of siRNA to target cells is the biggest challenge...

Full description

Bibliographic Details
Main Author: Lui, Wei-Li
Published: University of Oxford 2008
Subjects:
616.99466
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490105
id ndltd-bl.uk-oai-ethos.bl.uk-490105
record_format oai_dc
spelling ndltd-bl.uk-oai-ethos.bl.uk-4901052015-03-20T06:25:42ZCervical epithelial-specific delivery of small interfering RNA (siRNA); potential therapy for cervical carcinomaLui, Wei-Li2008KNA interference (RNAi) is a ubiquitous gene silencing mechanism, in which small interfering RNAs (siRNAs) guide sequence-specific cleavage of mRNA transcripts. Since naked siRNAs are inefficiently internalised by mammalian cells, successful delivery of siRNA to target cells is the biggest challenge for therapeutic application.616.99466University of Oxfordhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490105Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 616.99466
spellingShingle 616.99466
Lui, Wei-Li
Cervical epithelial-specific delivery of small interfering RNA (siRNA); potential therapy for cervical carcinoma
description KNA interference (RNAi) is a ubiquitous gene silencing mechanism, in which small interfering RNAs (siRNAs) guide sequence-specific cleavage of mRNA transcripts. Since naked siRNAs are inefficiently internalised by mammalian cells, successful delivery of siRNA to target cells is the biggest challenge for therapeutic application.
author Lui, Wei-Li
author_facet Lui, Wei-Li
author_sort Lui, Wei-Li
title Cervical epithelial-specific delivery of small interfering RNA (siRNA); potential therapy for cervical carcinoma
title_short Cervical epithelial-specific delivery of small interfering RNA (siRNA); potential therapy for cervical carcinoma
title_full Cervical epithelial-specific delivery of small interfering RNA (siRNA); potential therapy for cervical carcinoma
title_fullStr Cervical epithelial-specific delivery of small interfering RNA (siRNA); potential therapy for cervical carcinoma
title_full_unstemmed Cervical epithelial-specific delivery of small interfering RNA (siRNA); potential therapy for cervical carcinoma
title_sort cervical epithelial-specific delivery of small interfering rna (sirna); potential therapy for cervical carcinoma
publisher University of Oxford
publishDate 2008
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490105
work_keys_str_mv AT luiweili cervicalepithelialspecificdeliveryofsmallinterferingrnasirnapotentialtherapyforcervicalcarcinoma
_version_ 1716796759040065536

Similar Items