The supF assay for understanding DNA adduct-induced mutagenesis : traditional application and development of a site-specific version

A primary aim of this study was to establish and utilise the supF assay to investigate the mutagenicity of the cancer drug tamoxifen in target endometrial cells. In particular, the supF assay was employed to ascertain the mutations caused by two model reactive intermediates of tamoxifen, alpha-aceto...

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Bibliographic Details
Main Author: Liapis, Evagelos
Published: University of Leicester 2007
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490758