Chemical synthesis and investigation of reactive drug metabolites
Bioactivation of drugs to their chemically reactive metabolites (CRMs), often leading to protein-drug conjugates, is a widely-known hypothesis of adverse drug reactions. However the direct evidence of this hypothesis is lacking. Therefore highly pure CRMs are of great interest to both academia and i...
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University of Liverpool
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490798 |