The role of the human tumour suppressor CYLD in Drosophila
The cylindromatosis gene cyld encodes a tumour suppressor that is mutated in tumours of human skin appendages (cylindromas). Cell culture studies have shown that the CYLD protein is a deubiquitinating enzyme, which negatively regulates NF-KB and JNK signalling in mammals. Despite extensive research...
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University of Oxford
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491496 |