NMR Studies of 3'-S-phosphorothiolate Modified Oligonucleotides

The structure-function relationship of nucleic acids is highly researched due to their , potential as therapeutics and bio-analytical tools. The structural effects of a subtle 3'-S-phosphorothiolate (3'-8) modification within DNA systems has been investigated here with regards to a role in...

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Bibliographic Details
Main Author: Jayakumar, Hannah Kate
Published: University of Leeds 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491745