Regulation and specificity of the human disulphide catalyst Ero1-La

The formation of disulphide bonds within many proteins, especially those that are secreted, is essential for their correct folding, stability and function. Disulphlde bonds are formed within the lumen of the Endoplasmic Reticulum (ER) in mammalian cells. Protein disulphide isomerase (PDI) oxidises c...

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Bibliographic Details
Main Author: Baker, Karl
Published: University of Manchester 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491846