In vivo study of the DNA-binding requirements of the haematopoietic transcription factor SCL (stem cell leukaemia) in erythropoiesis
The bHLH (basic helix-loop-helix) transcription factor SCL (Stem Cell Leukaemia) is required for HSC (haematopoietic stem cell) specification and for differentiation of the megakaryocytic and erythroid lineages. bHLH proteins bind DNA as dimers and this has been thought to be a prerequisite for thei...
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University of Oxford
2006
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492059 |