Heterologous regulation of ADP and thromboxane receptors on human platelets
Thromboxane A2 (TXA2) and ADP are both major positive feedback mediators of platelet activation and act through G-protein coupled receptors (GPCRs) on the platelet surface. Aspirin and clopidogrel, two of the main drugs used in the prevention of acute coronary syndromes, function by blocking the act...
| Main Author: | |
|---|---|
| Published: |
University of Bristol
2008
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492443 |