Intracellular delivery of MDR drugs
One of the most important mechanisms for multidrug resistance (MDR) phenotype is believed be the P-gp-mediated drug efflux. The consequent lowering of the intracellular concentrations of many commonly-used chemotherapeutic drugs, such as doxorubicin (Dox), has been addressed by P-gp inhibition via c...
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University of Manchester
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492718 |