Cren- and euryarchaeal DNA polymerases : interactions with deaminated bases
The family B DNA polymerase from the euryarchaeote, Pyrococcus furiosus (PFU-Pol), has been shown to recognize template strand uracil and stall DNA synthesis four bases ahead, thus preventing the permanent fixation of the mutation. This recognition is due to the presence of a special pocket in the N...
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University of Newcastle Upon Tyne
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493030 |