Pharmacogentic factors influencing the metabolism of 13-cis retinoic acid

5203 L $$aThe administration of 13-cis retinoic acid (13cisRA) improves 3-year event free survival rates in children with high-risk neuroblastoma. However, more than half of patients suffer relapse within 3 years. A high degree of variability in UcisRA pharmacokinetics has been reported, suggesting...

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Bibliographic Details
Main Author: Rowbotham, Sophie E.
Published: University of Newcastle upon Tyne 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493211