An investigation into the ligand dependent regulation of the nuclear receptor PXR (NR1I2) and its target genes

The study of absorption, distribution, metabolism and excretion (ADME) of compounds within the body is of vital importance to health. PXR is a nuclear receptor which regulates the expression of a great many ADME genes and is responsible for the regulation of all parts of the ADME of many compounds....

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Bibliographic Details
Main Author: Bailey, Ian
Published: University of Surrey 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493227