Role of replisome proteins in recognition of deaminated bases in Archaea
Family B DNA polymerases from archaea, such as Pyrococcus furiosus (Pfli-Pol), stall replication upon encountering template strand uracil and hypoxanthine (the deamination products of cytosine and adenine spectively) four base pairs ahead of the primer template junction. The deaminated bases bind to...
| Main Author: | |
|---|---|
| Published: |
University of Newcastle Upon Tyne
2008
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493233 |