In silico investigation of amyloid

Amyloid fibrils, highly ordered aggregates of mis-folded protein with a characteristic cross-beta structure, are associated with several diseases including Alzheimer's disease and the prion diseases. Amyloid fibrils are difficult to study experimentally and there is litde high resolution struct...

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Bibliographic Details
Main Author: Clarke, Oliver James
Published: University of Leeds 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493763