ST2 & TLRs : coordination of chemokine-driven immunity

Abstract The detection of pathogen-associated molecules by Toll-like receptors (TLRs) is instrumental to the induction and regulation of an inflammatory response. However, prolonged or inappropriate stimulation of TLRs is associated with disease. A family of molecules coded for by the ST2 gene have...

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Bibliographic Details
Main Author: Moore, Mark
Published: University of Glasgow 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495484