Human aldosterone synthase and 11[beta]-hydroxylase : studies on the relationship of structure and function and their clinical implications
Abnormalities in adrenal steroid production have been implicated in certain forms of hypertension. Mutations in the CYP11B1 gene which result in complete loss of 11-hydroxylase function cause 11-hydroxylase deficiency and hypertension due to abnormally high levels of mineralocorticoid, DOC. Mutation...
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University of Glasgow
1999
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495635 |