Investigating the role of 53BP1 in DNA double strand break repair and checkpoint signalling
DNA double strand breaks arise endogenously in the cell as a result of routine activities such as metabolism and also as a result of exposure to exogenous agents such as ionising radiation. Repair of DNA DSBs is coordinated by two major repair pathways in mammalian cells; non-homologous end joining...
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University of Sussex
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496789 |