Fine mapping of quantitative trait loci (QTL) and identification of candidate genes for prion disease incubation in mice

Prion diseases are progressive neurodegenerative diseases which show characteristic prolonged incubation periods. Polymorphisms in the prion protein gene are known to influence incubation time but additional genetic loci have also been identified by quantitative trait locus mapping studies in mice....

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Bibliographic Details
Main Author: O'Shea, Marie
Published: University College London (University of London) 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498070