Effect of insulin-like growth factor binding protein-4 gene therapy on adenocarcinoma of the colon
Insulin-like growth factors induce the proliferation of transformed cells. IGF binding proteins (IGFBP) are involved in their local tissue regulation. In this project, the effects of early and late administration of IGFBP-4 gene were assessed on colon cancer model in vivo. Nude mice were subcutaneou...
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University College London (University of London)
2008
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498368 |