Hyperpolarisation-activated ion channels as a target for nitric oxide-cGMP signalling in the rat brain

Most of the known physiological effects of nitric oxide (NO) in the brain are mediated by activation of specialised guanylyl cyclase-coupled receptors, leading to a rise in intracellular cGMP. Apart from protein kinase activation little is known about subsequent cGMP signal transduction. In optic ne...

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Bibliographic Details
Main Author: Wilson, Gary William
Published: University College London (University of London) 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498498