Identification of genes regulating glucocorticoid-induced and antigen-mediated thymocyte apoptosis

The default pathway for developing thymocytes is apoptosis they must be actively instructed to survive and proliferate. Approximately 95% of developing thymocytes undergo apoptosis only 5% survive to enter the periphery. Thymocytes commit to apoptosis either because of a lack of survival signalling...

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Bibliographic Details
Main Author: Woodward, Martin James
Published: University College London (University of London) 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498911