Insight into homologous recombination at replication blocking lesions through analysis of the C. elegans RAD-51 paralog, RFS-1

The ability to sense and repair replication blocking DNA damage is a critical task for a cell, as evidenced by the embryonic lethality or cancer predisposition caused by mutation in any of these processes. Recent work has implicated homologous recombinational repair (HRR) as a key player in promotin...

Full description

Bibliographic Details
Main Author: Ward, Jordan David
Published: University College London (University of London) 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499038