Mucoadhesion of chitosan and derivatives : from mechanism to dosage form design : understanding of chitosan solubility parameters, interactions with mucosal membranes and BCS class II drugs in formulations, targeting enhanced permeation and increased bioavailability of poorly absorbable drugs

Chitosan is a natural polysaccharide produced commercially from chitin by partial deacetylation. It consists of glucosamine and Al-acetyl glucosamine units chained through glycosidic bonds. Due to the biocompatible and mucoadhesive profile it presents, it has attracted considerable attention for pot...

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Bibliographic Details
Main Author: Sogias, Ioannis Andrea
Published: University of Reading 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499371