Interaction of hemoglobin, nitric oxide and the stress protein haem oxygenase-1 : functional implications in sickle cell disease
Haemoglobin and nitric oxide (NO) strongly induce the stress protein haem oxygenase-1 (HO-1), which degrades haem to carbon monoxide (CO), a signalling and vasoactive molecule, the anti-oxidant biliverdin (BV) and iron. Raised HO-1 levels have been detected in the endothelium and kidneys of animals,...
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University College London (University of London)
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500150 |