Regulation of sterol regulatory element binding protein (SREBP) by the PI3-kinase/Akt pathway and its role in the regulation of cell growth

Protein kinase B (PKB/Akt) is a central component of intracellular signaling pathways. It becomes activated downstream of growth factor receptors and has been implicated in cell growth, proliferation and protection from apoptosis. Akt is also a mediator of metabolic insulin action, and stimulates gl...

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Bibliographic Details
Main Author: Porstmann, Thomas
Published: University College London (University of London) 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500318