Collagnase alone or in combination in the preparation of isolated rat hepatocyte? : the effect on the uptake, metabolism and efflux of xenobiotics

Isolated hepatocytes are one of the most relevant and practical in vitro models for the study of xenobiotic transport and metabolism. Several modifications of the original two-stage collagenase perfusion technique for the preparation of isolated hepatocytes exist. However, there are limited data abo...

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Bibliographic Details
Main Author: Sinclair, Julie Anne
Published: University of Strathclyde 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501873