The effect and interactions of the minor groove binders AIK 19/56/2 and AIK 20/25/1 on bacterial, fungal and mammalian cells

Minor Groove Binders are a group of compound that bind to the minor grooves of DNA. Some of these compounds are able to bind to specific sequences on DNA, causing toxicity to cells, and this has generated an interest in their use as antimicrobial or anticancer agents. They are generally characterise...

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Bibliographic Details
Main Author: Imtiaz, Nashmya
Published: University of Strathclyde 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502307