The pro-inflammatory role of copper in chemokine multimerisation and the potential of copper chelators as anti-inflammatory agents

Since both copper and dityrosine links have been implicated in the multimerisation of the amyloid protein in Alzheimer's disease, chemokines including RANTES, IL-8 and ENA-78 were investigated for the possibility of copper-induced dityrosine formation within chemokine multimers. The addition of...

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Bibliographic Details
Main Author: MacGregor, Helen Jane
Published: University of Portsmouth 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502734