Synthesis of phosphinic acid analogues of anti-tumour agents

Synthetic ether analogues (prototypes: miltefosine, perifosine and cdelfosine) of natural phospholipids are a family of anti-cancer drugs with a wide range of pharmacological behaviour. There is a growing interest in anti-cancer ether phospholipids owing to their seleC;!1vity against tumours which h...

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Bibliographic Details
Main Author: Markoulides, Marios Savva
Published: University of Manchester 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505383