Gene expression profiling of the response to physiological and environmental stress in motor neurones

Amyotrophic Lateral Sclerosis (ALS) is characterised by motor neuronal degeneration leading to muscular wasting and eventually death. 5% of ALS cases are familial (F ALS) and 20% of these are due to mutations in the gene encoding for copperlzinc superoxide dismutase-l (SOD1). Mice overexpressing hum...

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Bibliographic Details
Main Author: Ferraiuolo, Laura
Published: University of Sheffield 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505434