Electrophysiological and molecular studies of SCN5A mutations related to sick sinus syndrome
SCN5A is the gene encoding the a subunit of the cardiac voltage-gated sodium channel, hNav1.5. The ionic current through this channel, which is responsible for the upstroke of the cardiac action potential, plays an important role in normal cardiac rhythm in the heart. Genetic defects of SCN5A have b...
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University of Manchester
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506243 |