Bayesian statistical methods for genetic association studies with case-control and cohort design

Large-scale genetic association studies are carried out with the hope of discovering single nucleotide polymorphisms involved in the etiology of complex diseases. We propose a coalescent-based model for association mapping which potentially increases the power to detect disease-susceptibility varian...

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Bibliographic Details
Main Author: Tachmazidou, Ioanna
Other Authors: De Iorio, Maria ; Richardson, Sylvia ; Stumpf, Michael
Published: Imperial College London 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506410