Bayesian statistical methods for genetic association studies with case-control and cohort design
Large-scale genetic association studies are carried out with the hope of discovering single nucleotide polymorphisms involved in the etiology of complex diseases. We propose a coalescent-based model for association mapping which potentially increases the power to detect disease-susceptibility varian...
Main Author: | Tachmazidou, Ioanna |
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Other Authors: | De Iorio, Maria ; Richardson, Sylvia ; Stumpf, Michael |
Published: |
Imperial College London
2008
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Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506410 |
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