The role of matrix metalloproteinases in the immunopathology of cerebral tuberculosis
Introduction: Central nervous system tuberculosis (CNS TB) has a high mortality. Microglial derived matrix metalloproteinases (MMPs) are implicated in the intense inflammatory response to Mycobacterium tuberculosis (M.tb) as the blood brain barrier is rich in MMP substrates. Methods: In a cellular m...
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Imperial College London
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506480 |