Pharmacogenetic analysis of Farnesyl diphosphate synthase (FPPS) and nitrogen-containing bisphosphonates

A proportion of patients with osteoporosis, Paget’s disease and bone associated cancers show no reduction in disease-indicating markers after treatment with N-BPs, and resistance to bisphosphonates has been documented . We have examined whether polymorphic or isoforms variation in the FPPS gene coul...

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Bibliographic Details
Main Author: Lowes, Christina
Published: University of Aberdeen 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509183