The folding, misfolding and aggregation of prions

Prion diseases are a group of fatal neurodegenerative disorders that include Creutzfeldt-Jakob Disease (CJD), Bovine Spongiform Encephalopathy (BSE) and scrapie, which are all associated with the misfolding of the cellular form of the prion protein, PrPC, into the disease associated isoform, PrPSc....

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Bibliographic Details
Main Author: Robinson, Philip John
Published: University of Warwick 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511471