The effect of cAMP elevation on intracellular signalling pathways in prostate epithelial cells

Chronic IL-6 signalling contributes to the pathophysiology of many diseases including prostate cancer. Relevant to prostate cancer is the ability of the pro-inflammatory cytokine IL-6 to activate the oncogenic signalling protein STAT3, thus inhibition of STAT3 activation is a popular avenue of resea...

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Bibliographic Details
Main Author: Jones, Sarah Elizabeth
Published: University of Glasgow 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512127