Analysis of the functions and interactions of RAD51 paralogues in Trypanosoma brucei

Trypanosoma brucei evades host acquired immunity by antigenic variation, involving periodic switches in the variant surface glycoprotein (VSG) coat. DNA recombination is critical in this process and a key component of homologous recombination, RAD51, also plays a role in VSG switching. T. brucei enc...

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Bibliographic Details
Main Author: Dobson, Rachel Pamela
Published: University of Glasgow 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.513031