Pancreatic duodenum homeobox 1 (PDX-1) phosphorylation in pancreatic β-cells
Pancreatic Duodenum Homeobox (PDX-1) is a homeodomain transcription factor and a key regulator of β-cell development and differentiation. In mice and humans, mutations of the Pdx1 gene in β-cells have been linked to MODY and type 2 diabetes. Therefore, the regulation of PDX-1 transcriptional activit...
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Imperial College London
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.513420 |