Hypoxia regulated responses in the pathogenesis of rheumatoid arthritis

Increased angiogenesis in the synovium is a hallmark of rheumatoid arthritis (RA), and is thought to be driven by the presence of both local regions of reduced oxygen tension (hypoxia) and inflammatory cytokines in the synovium. RA fibroblast-like synoviocytes (FLS) are the main cell type at the pro...

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Bibliographic Details
Main Author: Larsen, Helene
Other Authors: Feldmann, Marc ; Paleolog, Ewa
Published: Imperial College London 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.513436