The role of vaccinia virus K7R gene in evasion of innate immunity

This thesis reports an investigation of the role of Vaccinia virus (VACV) gene K7R in evasion of innate immunity. The K7 protein is an inhibitor of intracellular signalling pathways leading to the activation of the innate immune response and was shown to act by inhibiting TBK1/IKK-ε - mediated IRF s...

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Bibliographic Details
Main Author: Bahsoun, Basma
Other Authors: Smith, Geoffrey
Published: Imperial College London 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.513639