EVI1 in Fanconi Anaemia-associated leukaemia : clinical relevance and functional insights

Fanconi Anaemia (FA) is an inherited genomic instability disorder caused by mutations in one of 13 FANe genes, the products of which interact to form the FABRCA pathway, which is involved in the cellular response to DNA damage. FA patients have a high risk of acute myeloid leukaemia (AML), implying...

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Bibliographic Details
Main Author: White, Daniel Jude
Published: University of Manchester 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.514398