EVI1 in Fanconi Anaemia-associated leukaemia : clinical relevance and functional insights
Fanconi Anaemia (FA) is an inherited genomic instability disorder caused by mutations in one of 13 FANe genes, the products of which interact to form the FABRCA pathway, which is involved in the cellular response to DNA damage. FA patients have a high risk of acute myeloid leukaemia (AML), implying...
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University of Manchester
2009
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.514398 |