An NMR and molecular modelling study on the solution conformation of Heparan Sulphate : new insights into the relationship between structure and function

A deeper insight into the structural biology of HS is key to understanding its nearuniversal functional role as a co-receptor for growth factors and morphogens. Due to the extreme difficulty in preparing homogeneous HS oligosaccharides for structural and functional studies, traditionally, oligosacch...

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Bibliographic Details
Main Author: Murphy, K. J.
Published: University of Huddersfield 2007
Subjects:
500
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516057