Associations of vitamin D receptor gene polymorphisms with multiple sclerosis risk, severity and spatial clustering
Introduction: The prevalence of multiple sclerosis (MS) shows a latitude gradient which may be related to exposure to ultraviolet radiation (UVR). The effects of UVR may be mediated through 1,25-dihydroxycholecalciferol which exerts its effects via the vitamin D receptor. We hypothesised that polymo...
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Keele University
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518335 |