Development of synthetic routes towards bis (macrocyclic) compounds for imaging and therapy of cancer

Porphyrin molecules are efficient generators of singlet oxygen and are used as photosensitisers in PDT. They are also known to accumulate in tumour tissue due to the hyperpermeability of tumour vasculature and poor lymphatic drainage, thus exhibiting a passive tumour targeting property. Functionalis...

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Bibliographic Details
Main Author: Welch, Chris J.
Other Authors: Boyle, Ross : Archibald, Stephen J.
Published: University of Hull 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.519199