Structural analysis of LMO2 for the development of a small molecule inhibitor

LMO2 is a nuclear LIM-only protein encoded by a gene located on chromosome 11p13 and was originally discovered through its activation due to specific chromosomal translocations in patients with T-cell acute lymphoblastic leukaemia (T-ALL). The specific chromosomal translocations occur with either th...

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Bibliographic Details
Main Author: Sewell, Helen
Other Authors: Rabbitts, T.
Published: University of Leeds 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.524509