Tumour delivery of anticancer agents via colloidal carriers constructed with P-glcoprotein inhibitory excipients
The poor aqueous-solubility of many anticancer drugs limits their use as therapeutic agents. PacIitaxel, for example, is extremely useful for many refractory cancers yet its poor aqueous-solubility «1IJg/mL) requires solubilisation in Cremophor® EL, the latter which presents many clinical side-effec...
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Kingston University
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.525864 |