Mutasynthesis approaches to the preparation of streptorubin B analogues
Prodiginines are a large family of red-pigmented tripyrrole-based antibiotics. Their biosynthesis in Streptomyces coelicolor A3(2), by enzymes encoded in the red gene cluster, involves the condensation of 4-methoxy-2,2′-bipyrrole-5- carboxaldehyde (MBC) and 2-undecylpyrrole, catalysed by the RedH en...
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University of Warwick
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527440 |